Access to adequate amounts of safe and nutritious food is essential for maintaining human life and health. Unsafe products, especially of animal origin, containing pathogens are the cause of many diseases that harm human health and affect the social state of society. Food safety is closely related to food safety, and the development and implementation of a system of control measures is an important task for any state. The article attempts to study the basic principles of building such a system at the first stages of its formation.

The modern food industry offers the consumer bread baked with sourdough using various biologically active components of plant origin. In the production of yeast-free bread, it is advisable to use a sourdough from biologically active strains of Streptococcus thermophilus selected by the Gorsk State Agricultural University. The authors have compiled a starter culture from local strains of lactic acid microorganisms selected by the Research Institute of Biotechnology of the Gorsky State Agrarian University. Research was carried out at the Department of Biological and Chemical Technology of the Gorsky State Agrarian University. We also used cones of wild-growing hops from the botanical garden of the Gorsky State Agrarian University in order that the bitter acids present in the hops suppress the putrefactive microflora, do not have a detrimental effect on local strains of lactic acid microorganisms and allow increasing the productivity of the hop starter culture. Yeast-free bread is easily absorbed by the body, does not harm the intestinal microflora, retains useful properties during storage. The flour used in the experiment met the requirements of GOST 26574–85. When using wild-growing hops in the production of bread, useful substances included in its composition were determined that could increase the quality and safety of bread. The content of alpha acids was 6.0%, and that of essential oils was 0.7%, which corresponds to GOST 32912–2014. We used two strains of a lactic acid microorganism of local selection – Streptococcus thermophilus. Hops were extracted for 30 min at a temperature of 96 °C. Laboratory baking of bread was carried out in accordance with GOST 27669–88. Studies have shown that bread prepared using a local strain of Streptococcus thermophilus selected by the Gorsky State Agricultural University and wild-growing hops is of high quality.

The priority route of entry of carcinogens into the body of the population of the Chelyabinsk region is oral, the leading medium for the transfer of xenobiotics is food, and the main carcinogen is arsenic, which comes from local agricultural products. The aim of the research was to study the mineral composition of semi-finished products from poultry meat from different manufacturing enterprises in the context of the environmental component of the safety of agricultural products. Chilled drumsticks produced by Nagaybaksky Poultry Complex LLC (Chelyabinsk Region, Nagaybaksky District, Farshampenuaz settlement) and Turbaslinskiye Broilers JSC (Republic of Bashkortostan, Blagoveshchensk) were used as objects of research. It was established that the maximum permissible concentration for arsenic was 3.7 times higher in the products of the Nagaybak poultry complex. Chromium was found more in semi-finished products from Bashkortostan (29 times), tin – in local raw materials. The drumsticks cooled from the Nagaybak processor significantly exceeded the competitor’s raw materials in terms of calcium (7.6 times), iron (2.9 times), zinc (2.1 times), selenium (2 times), phosphorus (1, 5 times), silicon (1.3 times), sodium (12.4%), as well as copper, manganese, molybdenum, tungsten, strontium. Relatively high levels of potassium (3.8 times) and magnesium (1.4 times), as well as aluminum, lithium, nickel, antimony, were recorded in the drumsticks of broiler chickens from a Bashkir producer. It was revealed that the semi-finished products of broiler chickens produced by Nagaybak Poultry Complex LLC did not comply with the requirements of Technical Regulation of the Customs Union 021/2011. The chilled shins of Bashkir production were recognized as safe within the framework of the current Technical Regulations.

The paper analyzes the literature on the therapeutic and prophylactic effects of components of secondary products of processing of rye and wheat – dietary fiber and phenolic compounds – on human health. A special role is played by soluble arabinoxylans and xylooligosaccharides associated with ferulic acid, which have prebiotic, antioxidant and immunomodulatory properties. Experimental and epidemiological studies have shown that the inclusion of cereal bran in the diet has a positive effect on human health and helps to reduce the risk of diseases associated with the Western type of diet – atherosclerosis, second type diabetes, and various types of oncology.

The applying of antibiotics in animal husbandry leads to the spread of antimicrobial resistant pathogens among domestic animals, which are subsequently transmitted to humans through the food chain. The analysis of literature data on the results of the study of phytochemicals of plant origin in the form of essential oils of medicinal and aromatic plants as one of the possible alternatives to feed antibiotics is presented. Such additives should reduce the incidence of animals by inhibiting pathogenic microflora, provide the animal with a larger amount of energy and nutrients by reducing the bacterial load in the intestine, reduce internal inflammatory processes by improving the immune system, and should be economically beneficial. A review of scientific studies showed that essential oils do have bactericidal properties, but their effect on the productive performance of animals still requires further research. Differences in animal productivity when using essential oils may be due to researchers using different doses, different test conditions (especially climatic conditions), and possible synergistic and antagonistic properties of essential oils with other feed substances.

The developed fortified products contain ingredients that are widely studied for a strictly defined set of macro-and micro-components that are deficient for the human body. However, the presence of additional unregulated elements in the enriching raw materials is not fully studied. In this context, the issue of a comprehensive study of not only the nutritional value, but also the element composition of raw materials that increase the nutritional density of the enriched product is relevant. The aim of the research was to study the safety and chemical composition of plant raw materials used to increase the nutrient density of food systems. Freeze-dried ground apples produced by PJSC Sibirsky gostinets (Pskov region, Moglino village) and Brazil nut kernels produced by Comservice LLC (Moscow region, Mytishchi) were used as research objects. It is established that the studied plant materials are safe for human health in terms of their elemental composition and microbiological indicators. The study of food density showed that ground apples did not correspond to the declared levels of protein and fat by 45,2 and 96,2%, respectively. However, Apple powder has a relatively high content of mineral elements Mo, Na, Si, Ga, B, sugar, starch, dietary fiber and organic acids, Brazil nut kernels-Mg, Se, Cu, P, CA, Mn, Zn, Fe, Co, Ni, Al, protein and lipids.

The article analyzes the state registration of specialized food products, using the example of food products for children from three years old. The research process involves certificates issued on the website of the «Unified register of state registration certificates’ in the period from 2014 to 2019. During the analysis, the main groups of specialized baby food were identified, and the number of registered certificates in dynamics was determined. The data obtained indicate that the demand for state registration of children’s specialty food increased by 2018 and amounted to more than 30% compared to the previous period. The most popular products on the market of baby food for children three years old: juice-containing beverages, including vegetable raw materials, vegetable nectars, fruit juices.

The modern Russian market is represented by a wide range of exotic types of plant products imported from different countries. Currently, there are more frequent cases when in fruits and vegetables there is an increased content of nitrates and toxic elements. Exotic types of plant products sold on food markets are allowed for sale only after passing veterinary and sanitary control in the State laboratories of veterinary and sanitary examination. The aim of the research was the veterinary and phytosanitary control of citrus fruits sold on the commodity market of the Chelyabinsk region. As the objects of research used fresh tangerines, oranges and pomelo, sold in the «Central Market» of Troitsk, Chelyabinsk region. It was found that only the labeling of the studied mandarin samples was complete and in accordance with the regulated requirements of the State Standard 51074–2003, Technical Regulations of the Customs Union 022/2011 and 005/2011. The organoleptic and physical characteristics of the tested samples were in accordance with the rules of the Rules for Veterinary Sanitary Expertise of Plant Food Products in the Veterinary Sanitary Expertise Laboratories of the Markets and the applicable State Standards – 4428–82, 4427–82, 34307–2017. Fresh tangerines, oranges and pomelo were safe for the content of lead, cadmium and nitrates in accordance with the norms of the Sanitary Rules and Norms 2.3.2.1078–01 and Technical Regulation of the Customs Union 021/2011. However, the amounts of lead and cadmium were more detected in the pulp, and the amount of nitrates was the same in the pulp and in the peel of citrus fruits.

Long-term data (2002–2019) on the conditions of the formation of Artemia populations in different types of hyperhaline lakes of the Altai Territory are analyzed. The boundaries of individual fecundity and average fecundity were calculated, the influence of abiotic factors on the quality content of ovisak was shown. The peculiarities of their changes at different levels of water salinity during the growing season have been investigated. The average number of litters (clutches) for Altai populations was calculated, the influence of environmental factors on this indicator was analyzed.

A method for solving the problem of protein and energy value of rations is presented, which seems to be a key task for workers in animal husbandry and agricultural science. An important place in it is given to legumes and oilseeds. They are widely used in feeding animals in the form of green fodder, natural, crushed seeds and products of their processing (cake, meal, oil, etc.) and, to a limited extent, in the composition of compound feed. A key issue in feed production is the problem of feed protein. The further development of animal husbandry depends on its solution. Protein deficiency in rations is usually up to 30%, and this leads to overconsumption of feed and increases the cost of livestock products by 1.5–2.0 times. The solution to the problem of fodder protein should be carried out mainly at the expense of leguminous crops and their mixtures, legumes. One of the main tasks of fodder production is the introduction of progressive harvesting techniques. Dry feed mixtures with their structure and shape most fully meet the physiological needs of animals due to the increased energy of nutrients and product quality.

The results of studying the influence of various biological and mineral fertilizers (Phytop 8.1, Phytop 8.67, AFG) on the yield and quality of fruits of the indeterminate Spock tomato variety are presented. During the study, phenological and morphological observations, accounting and evaluation of the quality of the obtained fruits, and analysis of the chemical composition of the fruits were carried out. The obtained data confirmed the positive impact of the use of biological preparations and nitrogen-containing fertilizers on the structure and quality of the resulting tomato crop, which will allow us to recommend methods and norms for applying fertilizer during the growing season.

Comfortable conditions for keeping animals are achieved on the basis of the requirements (provisions) of the basic biological law on the unity of the organism and the conditions of its existence, i. e. in the case of syintegration of all the links providing the industrial breeding of animals and birds.

The features of the rehabilitation of the immune system of piglets after weaning were studied in connection with different seasons of farrowing. To fulfill this goal, 4 groups were formed from the offspring of sows of the SM-1 breed of Novosibirsk selection. The 1st group included piglets from winter farrowings, and the 2nd, 3rd and 4th groups, respectively, young animals born in spring, summer and autumn. Each group consisted of 30 animals. Studies of indicators of the immune status were carried out before weaning and 30 days after weaning. Weaning of piglets from sows with their subsequent regrouping in the educational farm «Tulinskoye» is carried out at the age of 60 days. The research results have shown that the state of the immune status of 2- and 3-month-old pigs is seasonal. Piglets born in autumn show the best indicators of leukopoiesis, T-, B-lymphopoiesis, the formation of functionally mature T-lymphocytes, activated T-lymphocytes and antitelogenesis. The second position in terms of the intensity of leukopoiesis, antitelogenesis and B-lymphopoiesis is occupied by young animals born in summer. Piglets raised in winter differ from their peers in a low level of IgM synthesis, while piglets born in spring have the lowest total numbers of T-lymphocytes, T-helper inductors, T-killer suppressors, B-lymphocytes and IgG. A month after weaning, animals, regardless of the season of birth, showed a statistically significant decrease in T-lymphopoiesis. The activity of the T-link of the immune system decreased most significantly in young animals obtained in spring. However, in contrast to their peers, youngsters born in the spring showed a statistically significant increase in blood IgM and IgG concentrations. In piglets born in winter, summer and autumn, the activity of IgM synthesis, on the contrary, decreased, while the formation of IgG remained at the same level.

The technological solution of a meat farm for 1000 cows of a broodstock with a three-round hotel of cows is presented. The first round is planned in january – march, the second round – in may – july and the third-from september to november. The goal of the development is to ensure regular production of beef during the year, obtained from the slaughter of 6–7-month-old steers and 8–9-month-old chicks, grown on suckling under mother cows to a live weight of 170–216 kg. The average daily growth of bulls – 800, heifers-700 g. the daily supply of meat will reach 62.4 c, an average of 2 c per day. The average level of profitability is 30.6%. New design and planning solutions for industrial buildings are proposed. The parameters of the feed zone of the farm and the need for in-farm equipment were determined. When developing the master plan of the farm, the following main zones were identified: production purposes, storage and preparation of feed, auxiliary production. For the use of loose keeping of animals, the structural scheme of buildings was chosen without internal supports. Keeping cows with calves in winter is loose on a deep non-replaceable litter. Unlike young animals, the delivery of adult animals for meat takes place in September – October. For the mechanization of production processes, there are two mixers, a mini-feed mill, auto-watering machines, ball drinkers with electric heating, a water dispenser, a straw roll shredder, and a machine for treating animals with a disinfectant solution.

The results of the assessment of the amino acid profile of the longest muscle of the back of the Kemerovo breed of pigs and its two-breed and three-breed crosses with commercial breeds are presented. The largest amount of amino acids is found in the meat of purebred animals in comparison with two- and threebreed animals. In terms of the content of such amino acids as phenylalanine, aspartic acid, serine, glutamic acid, purebred animals significantly exceeded hybrids. It was shown that the studied groups of animals for all amino acids exceeded the FAO reference values, with the exception of lysine. The influence of gender on the amino acid composition of meat in purebred animals was revealed, since boars significantly exceeded pigs in 8 amino acids out of 17 studied. Reliable correlation coefficients were established between the content of a number of amino acids in meat samples, which coincide in all groups of pigs.