To preserve the Siberian roe deer, the most vulnerable species of the deer family, in conditions of high snow conditions, integrated methods of its biotechnical protection are necessary. The involvement of fallow lands in the biotechnical crop rotation, the creation of large forage areas is the basic basis for the conservation of this biological species in the anomalously critical periods of the winter cycle.

 The main groups of biologically active substances contained in the bark of Betula pendula were determined by the spectrophotometric method: triterpene saponins, coumarins, hydroxycinnamic acids, tannins. It was found that the place of growth affects the content of triterpene saponins. There is an increase in their content from the anthropogenic load. A comparative analysis of the quantitative content of coumarins in samples of birch bark showed the similarity of indicators, so we can conclude that the place of growth does not significantly affect the content of coumarins. Studies have shown that all the samples under study accumulate approximately the same amount (about 1.5 %) of hydroxycinnamic acids. The difference between the content of the studied substances is small, but it exists. Studies of the content of tannins found that the place of growth of the hanging birch does not significantly affect this indicator. But with the increase in anthropogenic impact, we can note an increase in the content of this group of BAS. The study of the content of amino acids showed that the area of growth of the hanging birch affects their content in the bark. Anthropogenic factors also affect the content of amino acids, with an increase in the anthropogenic load on the growing area, the content of amino acids becomes higher.

 Wheat bread remains in the diet not only of Russians, but also of the population of other countries as a daily product, which makes it possible to consider it as an object for modifying the chemical composition and nutritional value in order to give it functional, dietary, or therapeutic and prophylactic properties. The purpose of the research is to study the composition of the functional components of non-traditional types of flour used in wheat bread technology in order to establish the effectiveness of their use. The objects of research were: bakery wheat flour of the highest grade, walnut flour, peanut flour, coconut flour. The analysis of organoleptic, physicochemical indicators and nutritional value of wheat bakery flour and various types of flour from walnut is carried out. An acceptable sensory compatibility of the studied raw material was established. Replacing a part of wheat flour in the recipe of bakery products with raw materials from peanuts or walnuts is a reasonable condition for eliminating the deficiency of dietary fiber in them. Increasing the biological value of products and the content of polyunsaturated fatty acids in it due to the use of peanut and coconut flour is of undeniable nutritional value. The source of phosphorus and copper can be considered flour from walnuts and peanuts; iron and selenium – walnut and coconut flour; magnesium and calcium – walnut flour. In a practical way, the effectiveness of replacing wheat flour in the recipe of bakery products with raw materials from nut-bearing raw materials has been established to increase the content of functional food ingredients in finished products. 

 A technology has been developed for the production of edible packaging based on applesauce with the addition of dried fruit and vegetable raw materials. As a result of research, a technology was developed for the production of edible glasses based on applesauce with the addition of dried apples, apricots, cranberries, bell peppers, tomatoes, carrots, and beets. A comparative assessment of the organoleptic and physico-chemical parameters of edible glasses based on applesauce with the addition of dried fruit and vegetable raw materials. Organoleptic indicators, humidity, water absorption, resistance to model liquids (distilled water with a temperature of 20–25 °C; distilled water with an initial temperature of 90–95 °C; 5 % aqueous solution of sodium chloride with a temperature of 20–25 °C; 5 % aqueous citric acid solution with a temperature of 20–25 °C), microscopic examination of the surface. Thus, as a result of a study of the organoleptic and physico-chemical parameters of edible packaging based on apple raw materials with the addition of dried fruit and vegetable raw materials, it was found that the most optimal physico-chemical indicators and mechanical properties of the glass are observed at the highest degree of grinding of dried fruit / vegetable additives and increase the degree of coverage of the surface area of   the edible glass with the additive. 

 Walnut flour is considered by food technology specialists as a source of complete protein, lipids, carbohydrates, minerals, vitamins, etc. The purpose of the research is to study the possibility of using walnut flour in the “Fitness” buckwheat bread technology in order to expand the range and increase the nutritional density of bakery products. The objects of research were: baking wheat flour of the first grade; walnut flour; bakery mix “Fitness Mix” buckwheat; control samples of “Fitness” buckwheat bread; experiment No 1 – replacing 15 % of wheat flour with an identical amount of walnut flour; experiment No 2 – with the replacement of 15 % of wheat flour with walnut flour and the replacement of 2 % of the bakery mixture with a similar amount of wheat gluten; experiment No 3 – with the replacement of 15 % of wheat flour with walnut flour and replacement of 4 % of the bakery mixture with wheat gluten; experiment No 4 – with the replacement of 15 % of wheat flour with walnut flour and the replacement of 6 % of the bakery mixture with wheat gluten. The quality and chemical composition of wheat flour, walnut flour and a mixture of bakery buckwheat were investigated. The superiority of walnut flour over wheat raw materials in terms of a number of nutrients was revealed. The priority role of wheat flour in the formation of porosity and the formation of the specific volume of bread is determined. Modification of the “Fitness” buckwheat bread recipe was carried out. 

 The article provides data review of relevant publications, presenting issue of current state of the dairy cattle breeding in Western Europe and Mountain Altai. The intensification of milk production and milk quota abolition weaken milk from mountain farms with regard to direct competition with milk produced on the plains. The consequence is the declining number of mountain farms in the Alps that has negative influence on the ecological and economic situation. There are difficulties in promotion dairy products in the market despite the fact that dairy products are produced in the mountains from grazing cows and have an increased biological value in human nutrition. As a mountain region, Altai Republic has dairy cattle breeding that developed successfully throughout the XX century similar to Swiss concept. However, in recent years the industry is also in crisis due to the low animal productivity and the high costs of fodder production and purchase. The article describes some ways to increase economic efficiency of the industry in the region, considering foreign experience and local specifics. 

 The article is devoted to the problem of consequences of anthropogenic environment pollution with heavy metals and their salts. The review presents data on food products that most actively accumulate them. It is shown that edible wild-growing and cultivated mushrooms are classified as such. At the same time, there are no normative documents regulating the maximum permissible values of heavy metals content for wild mushrooms. Herewith, among the wild-growing mushrooms, there are species that are most prone to the heavy metals accumulation. According to the authors, the issue of studying the accumulation of heavy metals by fungi growing near cities with developed industry is relevant. It is required to develop methodological approaches for their detection in wild-growing edible mushrooms and regulatory documents regulating their admission to the retail network. 

The results of studying the influence of various biological and mineral fertilizers: Phytop 8.67, Agrofit-humate-B (BKG «AFG-B”) – on the growth and development of plants, as well as the yield and quality of kiwano fruits of the Green Dragon variety are presented. During the study, phenological and morphological observations, accounting and evaluation of the quality of the obtained fruits, analysis of the chemical composition of the fruits were carried out. The obtained data confirmed the positive effect of the use of biological preparations on the structure and quality of the resulting crop of kiwano, which will allow us to recommend this crop for cultivation in the territory of the Novosibirsk region, using experimentally proven methods and norms of fertilizer application during the growing season of plants.

The problem of the formation of leukemoid reactions in cattle is considered. It is noted that such changes in the morphological composition of blood are most often characterized by a decrease in the quantitative content of lymphocytes while increasing the concentration of microphages (neutrophils). With the elimination of the cause that caused the manifestation of the leukemoid reaction of the blood, the morphological composition of the peripheral blood is restored to normal. 

One of the most important aspects of maintaining the health of animals is to meet their needs for nutrients, vitamins and minerals. To solve this problem, it is necessary to optimize the diets of animals. However, when talking about the territory of the Altai Territory, it should be borne in mind that the soil and, accordingly, the plants growing on it, can not meet the need of cattle in such a trace element as iodine. It is obvious that it is necessary to introduce a qualitatively new way to solve this problem in cows. The most productive, in our opinion, is the method of subcutaneous administration of Kayod tablets. Testing of this method was carried out on pregnant cows of the uchkhoz «Prigorodny». Three groups of pregnant cows with 15 animals each were formed for the research. A preliminary analysis of the diet was made, according to which the iodine deficiency was 15 % per animal. During the experiment, cows of different groups were implanted under the skin with Kaiod tablets in different dosages, after which the hormonal parameters of the cows « blood were examined to determine the content of thyroxine and triiodothyronine in it. The study of the dynamics of these indicators most clearly characterizes the presence or absence of hidden pathological processes in the animal’s body that affect the metabolism, and, accordingly, are directly related to iodine deficiency or its absence. Based on the above, it is necessary to conclude that the use of Kaiod tablets in cows during pregnancy in the form of subcutaneous implants according to the method developed and implemented by the authors is a very productive way to normalize the function of the thyroid gland in cattle. The correction of the metabolism begins immediately after the implantation of the tablets and continues to work for 2–3 months in the future. 

 The assessment of cattle of black-and-white, red steppe, Simmental breeds, differentiated by live weight, was carried out. Three groups were formed: selection, production, and marriage. The selection parameters are calculated using the standard deviation. The calculated parameters of selection of animals of breeding groups by live weight in full-aged cows of the black-and-white breed are 527–472 kg, red steppe-595–514, Simmental breed from the Novosibirsk region – 555–447, the Republic of Khakassia – 610–475, Hereford – 570–462 kg. The animals of the breeding group of the black-and – white breed have an average live weight of 552.5 kg, the red steppe – 641.1 kg, the Simmental Novosibirsk region – 576.7 kg, the Republic of Khakassia – 648 kg, and the Hereford Region-591.1 kg. The analysis of interbreed differences of cows of breeding groups shows that animals of Simmental and Red steppe breeds surpass their peers in most measurements. Animals of the black-and-white breed are the leaders in milk yield and milk content index, Red steppe-in milk fat content and milk fat, Simmental cows bred in the Republic of Khakassia – in live weight. The assessment of production groups of animals by live weight allows us to note that the black-and-white breed surpasses its peers in milk productivity and is characterized by broadness; the red steppe breed – by live weight and fat content of milk and is characterized by elongation; the Simmental breed has a greater development of high-altitude measurements. Evaluation of breeding groups of animals by live weight allows us to note its relationship with other productive traits. The formation of a breeding group with a high live weight allows you to create a tall and stretched array of cattle. 

The immune system of 90-day old piglets of SM-1 Novosibirsk breed piglets depends on sex and stress-reactivity. Stress-reactivity was measured using halothane test. The immunologic testing was performed 30 days after weaning. Our results show that overall piglet immune system demonstrated high proliferative activity of T- and B- immunocompetent cells with active formation of mature active T-and B-lymphocytes and did not show signs of immunosuppression. Compared to guilts, barrows had higher concentration of leucocytes, T-and B-lymphocytes, killer-supressor T-cells, activated and poorly differentiated T-lymphocytes. Gilts had higher production of inductor-helper T-cells, IgM and IgG when compared to barrows. Stress-resistant piglets had higher concentration of B-lymphocytes, IgM and IgG whereas stress-sensitive piglets had higher concentration of T-lymphocytes, supressor-killer T-cells and thymus T-lymphocytes. Gilts had higher concentration of inductor-helper T-cells than killer-supressor T-cells. Gilts overall had intensive antibody synthesis, however, stress-resistant gilts had higher IgG synthesis compared to stress-sensitive gilts. In barrows immature T-lymphocytes differentiated mainly into killer-supressor T-cells. The adaptivity of barrow immune system was characterized by high circulatory B-lymphocytes and IgM. Stress-sensitive barrows had lower antibody synthesis levels and higher T-lymphophoesis compared to stress-resistant barrows. 

 Over the period of research from 2003 to 2019 years, only 247 foci of leptospirosis of animals were registered in Yakutia, including: cattle – 61 (25.5 %), horses –159 (65.4 %), pigs –13 (5.3 %), small cattle – 8 (3.2 %), fur animals – 1 (0.4 %), bison – 4 (1.6 %). At the same time, a significant part of the foci of leptospirosis falls on horse breeding – 65.4 %. The largest number of disadvantaged points was established in 2008–49, including in horse breeding farms – 34 (69.4 %). An increase in the spread of the disease can be observed from 2003 to 2008 with a frequency of two years, and from 2008 – four years. Over the past 15 years, the introduction of leptospirosis pathogens has been established in 29 districts of the republic. It has been established that in the republic the main circulating serogroups of leptospirare Hebdomadis, Tarassovi, Icterohaemorrahagiae, Grippotyphosa, Canicola and Pomona. In zones of local economic stress, the source for the emergence and spread of leptospirosis are farms with a high number of farm animals. Of particular note are epizootic manifestations of leptospirosis in the Central Zone, which currently accounted for 80 % of the total quantity, in the remaining zones ranges from 2.5 to 7.5 %. It was revealed that the largest number of positive results was revealed in the spring period from April to June, and in the winter period – from November to December.