Industrial enterprises, automobile transport, every year more and more polluting hazardous wastes. Increasingly, vegetables, fruits, berries, mushrooms, grains, meat and other animal products, above acceptable norms detect lead, arsenic, sulfur, phosphorus, cadmium and other hazardous substances. So everywhere on the first place in the food production problem is the problem of the production of environmentally friendly products supply.

Applicability of veterinary enterosorbents of different nature is represented in review. The significance of enterosorbents and prospects of developing new medicinal products for animal use are justified.

The article presents data characterizing the peculiarities of the formation of the immune system of piglets obtained from ewes with different number of spolocnosti. In days age of piglets obtained from sows check differ from the offspring of ewes of the second and third farrowing, higher blood levels of leukocytes, undifferentiated thymic T-lymphocytes, activated T- lymphocytes and low levels of colostral antibodies, lymphocytes, T-killers-suppressor and B lymphocytes. In the 30 and 60 days of age the young are received from the check dams, characterized by the most intensive synthesis of IgM and low IgG level of education. The highest level of synthesis of IgG in these age periods shows the third offspring of sows farrowing.

The article presents the technology of tincture obtaining from various medicinal plants compositions. In the prepared tinctures were discovered biologically active substances with immunomodulatory actions. It was shown that the tincture of the first composition had immune stimulating effect on cellular immunity, increasing the functional activity of T-lymphocytes in the development of oncological process after irradiation of animals with sub-lethal dose of radiation at a dose of 6Gy. Tincture of the second herbal composition of experimental animals with oncological process has immunomodulatory effect on the functional status of cellular immunity, supporting them to the level of the intact organism. The technology of production of fermented milk drink immunomodulatory actions with the use of this tincture was developed. A new fermented milk drink is characterized by high consumer properties and can be recommended for mass consumption, and as an immune modulator for deterministic population groups whose immune system has been weakened due to some or other reasons.

Physiologically active fractions of proteins extracted from plants of the wheat buffer and determined their activity with different conformational agents. Higher activity was shown by fractions of proteins, determined with potassium chloride. Xenobiotics are most strongly activated ion-bound fractions form the physiologically active proteins of wheat plants. Using chromatography we studied the influence of xenobiotics on the amino acid composition of wheat plants. It is established that the amino acid composition of proteins in wheat plants during the growing season included free and bound, including essential and nonessential amino acids. The most significant influence xenobiotics have on free and bound tryptophan wheat, which is an essential amino acid. In the grain of durum wheat grown in conditions of use of xenobiotics, increased protein content and gluten has improved the quality of dough and bread. Rheological properties of gluten (elasticity, flexibility), largely determine the baking advantage of wheat flour were improved by the action of xenobiotics.

The results of study of influence of properties of feed concentrate Zesco against the microorganisms: the strains E. coli, Staphylococcus aureus and the fungus Fusarium sporotrichinella. Presents the results of the sorption capacity of the concentrate in relation to mycotoxin B1 Studied the effect of feed concentrate on the background of experimental mycotoxicosis, T-2. The use of natural fodder concentrate Zesco chickens when feeding them contaminated with the mycotoxin T-2 feed resulted in increased weight gain and positive effect on the internal organs and blood biochemical parameters of the organism. In studying the effect of forage concentrate Zesco on the effectiveness and duration of subclinical mycotoxicosis found that over 63 days of experience on the chickens with 100 % of the safety gains in the group, where the feed was added 5 % Zesco and 6 % of cultures of the fungus Fusarium sporotrichinella (616 mg/kg T-2), the increase of live weight of chicken was 2.7 % more than in the control group and 12 % of the group, where the feed was added 6 % of a culture of the fungus without concentrate. Data of the experiment prove the preventive, detoxification effect of feed concentrate Zesco subclinical mycotoxicosis in long-term use, and it gives the basis for carrying out production tests.

The daily addition of a new bio-supplement, rye germ flour, to a basal balanced diet for bred sows on the basis of 150 g per day from the 30th to 104th days of their pregnancy allows normalizing their reproductive function. The bio-supplement contributes to improving the beneficial use of sows. The level of infertile services in the control group made up 25.0 percent of the number of serviced sows; in the test group only 8.2 percent of sows were retired for this reason. It was established that multifetation in sows increased by 0.73 piglets, the numbers of dead born and weak born piglets reduced by 0.34 and 0.36 animal units, respectively; output of big-weight sucking pigs increased by 9.95 percent; live weight of litter at birth increased by 11.6 percent. The piglets obtained from such sows had higher productive qualities and safety as compared with the litters in the control group.

One of the main causes of economic losses in cattle are the respiratory diseases of young cattle. Most often the development of widespread diseases in the household promotes the wrong approach to keeping and feeding of cattle, as well as a clear planning of veterinary measures and targeted therapeutic and preventive work on the part of veterinary professionals Respiratory diseases calves are one of the major veterinary problems in specialized fattening farms all over the world. Most often the signs of such diseases are manifested at the age of 35-45 days the result of the expenditure of colostral protective factors. Characteristic features of the disease are coughing and sneezing, secretion from the nasal cavity of serous fluid. Such animals after recovery is slowly recovering efficiency, they lag behind in growth and development, and usually remain latent carriers of the pathogen. At the moment, the most promising direction is their prevention of immunomodulatory drugs and cleanliness in the room, no drafts and dampness, that is, compliance with sanitary and veterinary standards for premises which contain calves. Drug Konergin is immune modulating.. It is developed by Closed Joint Stock « Rosvetfarm « and is offered for the prevention of respiratory disease of calves 1-3 months of age, but also enhance the vitality of newborn calves, contains a synthetic glycosides antiviral action, vitamins, stimulants of physiological processes and organism resistance. According to the developer in subcutaneous administration the drug does not cause a pain reaction, has no side effects, is not toxic. After a single injection of Konergin its preventive effect persisted up to 2 weeks. The analysis of the obtained results was an increase in phagocytic activity of neutrophils in calves with the use of the drug Konergin that really indicates immunostimulating effect.

Conducted research of peculiarities of adaptation of imported cattle Kholmogory breed to extreme conditions of Yakutia. It is revealed that all clinical parameters in the studied groups of animals correspond to physiological norms. From imported cows observed increased frequency of pulse and respiration as compared to data from adapted cows. The temperature of the body in both compared groups was virtually identical and built from imported cows of 38.3±0.1 °C, adapted to 38.1±0,19 °C. From imported animals as a result of increased exposure to stressors in the new environment maintain homeostasis, accompanied by a significant activation of morphological and metabolic processes in the body.

In this paper we consider one of the basic types in the feed diet of reindeer is lichen. It is known that the diet of domesticated reindeer includes more than 440 species of plants. However, despite the large species diversity of plant feed, homemade reindeer, unlike in the wild, eating much more yagel feed. The lichen flora of Yakutia includes 703 species and 10 species of lichens belonging to 173 genera, 57 families and 13 orders. Most of them often eat deer lichen species are members of the family Cladoniaсеае, comprising 50 species. Due to the mass distribution of these lichen species are in the diet of reindeer 75-90 % by weight of edible lichen. It is revealed that the total protein level and protein fractions in the blood serum of domesticated reindeer vary depending on season and area of their breeding.

The epizootic situation of pseudomonosis of young pigs was analyzed from 1990 to 2016, the main parameters of the epizootic process of this infection in the conditions of pig farms in the Krasnodar region were determined.

Studied the problems and prospects of development of milk horse breeding in Yakutia.

Examined publishing activities in the field of production of agricultural literature in Eastern Siberia in the early XX century. The typology and subject matter of publications. The work provides statistical tables.

The Us within 5 years the features of the bees on two types of dandelions: drug (Taraxasum officinale) and late (Taraxacum serotinum) in the forest-steppe zone of the Kemerovo region and in the North of the Novosibirsk region (the area of the Vasyugan swamps). Nectarinidae dandelion maximum at a temperature of 24-28 °C. In contrast to the forest of the South, in the Northern latitudes of Siberia the flow of nectar and pollen of the dandelion was no more than 2 kg per day. Stored spring feed with dandelion was used by the bees to the chief a bribe, and the bee colony marketable honey is not allowed. Biochemical analysis of dandelion honey has shown its high quality indicators, humidity 17 %, diastase number - 15,9 units GOTHA (at the rate of 7) and the mass fraction of reducing sugars 86 % (at a rate of not less than 80 %).

This paper examines the effect of bacterization of seeds of spring wheat microbial drug Baxim and its impact on the growth and development of culture under different levels of fertilizer of the soil.

The results show that the development of calves is positively influenced by the feeding of mineral elements and vitamins. The calves of the 3rd group, which received mineral supplements and tetravit, to the end of the milk period, had a live weight 165,1 kg, they were superior to peers 2 nd experimental and control groups 9.3 and 26.3 kg, respectively. The use of mineral supplements and injections terravita contributed to the improvement of the morphological composition of blood of the experimental animals, the amount of hemoglobin increased in the 2nd group at 3.2 g/l, 3rd 8.4 g/l compared to control. Thus, salts of mineral elements separately or in combination with injections of terravita stimulates the growth and development of calves.