Biological activity of probiotic microorganisms depending on cultivation conditions
https://doi.org/10.31677/2311-0651-2024-43-1-78-86
Abstract
Metabiotics, a new generation of probiotics based on biologically active components (metabolites), are currently the subject of interest and study in the scientific community. This is a more advanced and promising form of probiotic preparations, among the properties of which high bioavailability, safety, and 'versatility in use are especially noted. The article presents a study of the antagonistic activity and biofilm formation of opportunistic strains of microorganisms under the influence of metabolites of probiotic microorganisms grown on 'various nutrient media and in different physical states. The objectives posed during the study answer questions about the biological activity of probiotic microorganisms grown on different nutrient media and in various physical states. The data obtained will form the basis for further research of active components that allow obtaining a clinical effect and will also help formulate an approach to developing the most effective ready-made forms of metabiotics. The place of research is the microbiological laboratory of the Testing Center of the Testing Laboratory Complex of the Federal State Budgetary Educational Institution of Higher Education Novosibirsk State Agrarian University.
About the Authors
V. V. Domnysheva
Novosibirsk State Agrarian University
Russian Federation
Russian Federation
PhD Student.
D. A. Domnyshev
Novosibirsk State Agrarian University
Russian Federation
Russian Federation
PhD in Technical Sciences.
Y. A. Gulyaeva
Novosibirsk State Agrarian University
Russian Federation
Russian Federation
PhD in Chemical Sciences.
A. N. Shvydkov
Novosibirsk State Agrarian University
Russian Federation
Russian Federation
Doctor of Agricultural Sciences.
A. I. Kalmykova
Novosibirsk State Agrarian University
Russian Federation
Russian Federation
Doctor of Biological Sciences, Professor.
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Review
For citations:
Domnysheva V.V., Domnyshev D.A., Gulyaeva Y.A., Shvydkov A.N., Kalmykova A.I. Biological activity of probiotic microorganisms depending on cultivation conditions. Innovations and Food Safety. 2024;(1):78-86. (In Russ.) https://doi.org/10.31677/2311-0651-2024-43-1-78-86
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