ENDOCRINOLOGICAL INTERRELATED DISEASES: CELIAC DISEASE AND DIABETES MELLITUS
https://doi.org/10.31677/2311-0651-2019-26-4-103-108
Abstract
<p>The results of the analytical review of scientific material presented in the article are devoted to the problem of intolerance of wheat protein gliadin in people with a predisposition to this food Allergy, as well as materials related to modern means against diabetes, based on the study of the endocrine system. The DPP-4 enzyme (dipeptidylpeptidase 4), which breaks down gluten protein in the human body, and the consequences of deficiency and excessive production of this enzyme in the form of chronic diseases (celiac disease and type II diabetes), were considered as one of the probable causes that combine these diseases. During the evaluation of the scientific material, the principle of determinism was applied to DPP-4, since this enzyme is the only one specifically interacting in the small intestine with gliadin and casein, and violations of the production and activity of this enzyme cause the appearance of gluten enteropathy. The review also presents data from foreign and Russian sources on the means for controlling diabetes based on substances that suppress the production of the enzyme DPP-4, hypersynthesis of which suppresses the production of insulin, which is one of the endocrinological causes of diabetes. Based on the studied data, it can be argued that the most positive and progressive solution to the problem of both chronic diseases is the method proposed by Japanese scientists, based on a special treatment of ginger root protease a, since, having the ability to break down gluten, this drug also leads to the suppression of dipeptidylpeptidase 4, while being a relatively affordable drug.</p>
About the Authors
K. A. Tabanyukhov
Siberian branch of the Federal state budgetary institution «Federal scientific center of food systems. V. M. Gorbatova» RAS; Novosibirsk State Agrarian University
Russian Federation
Graduate Student
Russian Federation
Graduate Student
V. A. Scryabin
Siberian branch of the Federal state budgetary institution «Federal scientific center of food systems. V. M. Gorbatova» RAS
Russian Federation
Candidate of Technical Sciences, Associate Professor
Russian Federation
Candidate of Technical Sciences, Associate Professor
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Review
For citations:
Tabanyukhov K.A., Scryabin V.A. ENDOCRINOLOGICAL INTERRELATED DISEASES: CELIAC DISEASE AND DIABETES MELLITUS. Innovations and Food Safety. 2019;(4):103-108. (In Russ.) https://doi.org/10.31677/2311-0651-2019-26-4-103-108
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