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BIOTECHNOLOGICAL PREPARATIONS FOR MEDICINE AND VETERINARY MEDICINE IN PROGRAMS PRODUCTION OF ENVIRONMENTALLY FRIENDLY FOOD

https://doi.org/10.31677/2311-0651-2019-26-4-69-80

Abstract

<p>A proposal is being considered for the use of BAS preparations developed in the Institute of medical biotechnology OF the FBU SSC VB «Vector» in the programs of ensuring the country’s security in the field of medicine, veterinary medicine and obtaining environmentally friendly food products. On the basis of biotechnological methods, a technology for obtaining a complex of biologically active preparations of double-stranded and single-stranded RNA from yeast and phages that can provide a solution to the above problems has been created. The» ideology «of the development consisted in a deep study of the EN-Dogen induction of interferons by the organism itself using evolutionarily formed mechanisms. The basis was taken of inter-veronicaceae mechanisms of action of viruses. Such drugs when injected into the human body and animals can act as viruses, inducing the synthesis of interferons and other proteins-cytokines in the body, but unlike viruses, they do not produce destructive effects. Activation of the endogenous cytokine network in this case at the systemic level can form a state of non-specific resistance against viruses, bacteria and their toxins. Injectable and ointment forms of these drugs based on RNA were developed, tested and approved by the Ministry of health of the Russian Federation and the Department of veterinary medicine of the Russian Federation. Introduction of effective methods of application of the developed preparations allows to use them as etiotropic means of emergency prevention and treatment of viral diseases of the person, calves, pigs, carnivores, birds and fishes, correction of immunodeficiency, strengthening of protective properties of vaccines.</p>

About the Authors

Yu. S. Alikin
Institute of Medical Biotechnology, State Research Center of Virology and Biotechnology «Vector»
Russian Federation
Doctor of Biological Sciences, Professor, Senior Research Fellow


M. V. Alekseeva
Institute of Medical Biotechnology, State Research Center of Virology and Biotechnology «Vector»
Russian Federation
Junior Researcher Fellow


V. V. Ermolaev
Institute of Medical Biotechnology, State Research Center of Virology and Biotechnology «Vector»
Russian Federation
Junior Researcher Fellow


V. P. Klimenko
Institute of Medical Biotechnology, State Research Center of Virology and Biotechnology «Vector»
Russian Federation
Researcher Fellow


L. R. Lebedev
Institute of Medical Biotechnology, State Research Center of Virology and Biotechnology «Vector»
Russian Federation
Doctor of Medicine, The Head of Laboratory


Yu. V. Telegina
Institute of Medical Biotechnology, State Research Center of Virology and Biotechnology «Vector»
Russian Federation
Junior Researcher Fellow


T. G. Tereshchenko
Institute of Medical Biotechnology, State Research Center of Virology and Biotechnology «Vector»
Russian Federation
Junior Researcher Fellow


A. Ya. Stolbov
Institute of Natural and Technical Systems
Russian Federation
Candidate of Biological Sciences, Senior Researcher Fellow


I. S. Shchelkunov
Institute of Medical Biotechnology, State Research Center of Virology and Biotechnology «Vector»
Russian Federation
Candidate of Biological Sciences, Senior Researcher Fellow


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Review

For citations:


Alikin Yu.S., Alekseeva M.V., Ermolaev V.V., Klimenko V.P., Lebedev L.R., Telegina Yu.V., Tereshchenko T.G., Stolbov A.Ya., Shchelkunov I.S. BIOTECHNOLOGICAL PREPARATIONS FOR MEDICINE AND VETERINARY MEDICINE IN PROGRAMS PRODUCTION OF ENVIRONMENTALLY FRIENDLY FOOD. Innovations and Food Safety. 2019;(4):69-80. (In Russ.) https://doi.org/10.31677/2311-0651-2019-26-4-69-80

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