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LYMPHOID ORGANS IN LEUKEMIA AND OTHER PATHOLOGIES IN CATTLE

https://doi.org/10.31677/2311-0651-2022-38-4-116-121

Abstract

Using the reaction of anaphylaxis with desensitization on guinea pigs, the antigenic structure of lymphoid organs in leukemia and other pathologies of cattle was studied. It is believed that neoplasia is the result of a distortion of the gene activity program due to the introduction of an oncogenic virus into the cell genome, integration with other biological objects, or gene mutation. All this leads to the emergence, first of all, of quantitative anomalies, expressed in continuous, uncontrolled cell division, cell migration and changes in their biochemical activity. In all likelihood, the essence of the identified differences described in the article is that in the biological fluids of cows with leukemia there are, in addition to BLV antigens, water-soluble leukemia-associated antigens.

About the Authors

P. N. Smirnov
Novosibirsk State Agrarian University
Russian Federation

Doctor of Veterinary Sciences, Professor



T. A. Agarkova
Siberian Federal Scientific Center of Agrobiotechnologies SB RAS
Russian Federation

Ph.D. in Veterinary Sciences, Associate Professor



V. V. Razumovskaya
Altai State Agrarian University
Russian Federation

Doctor of Veterinary Sciences



References

1. Zil’ber L.A. Osnovy immuniteta (Basics of immunity), Moscow: Medgiz, 1948, 494 p.

2. Zil’ber L.A., Abelev G.I. Virusologiya i immunologiya raka (Virology and immunology of cancer), Moscow: Medgiz, 1962, 457 p.

3. Parnes V.A. Immunologiya lejkoza (Immunology of leukemia), Moscow: Medgiz, 1960, 242 p.

4. Vardosanidze E.Sh., Menedriya V.V., Materialy sovetsko-bolgarskogo simpoziuma po immunologii opuholej, Moscow, 1973, pp. 8–9. (In Russ.)

5. Zatula D.G. Skhodstvo antigenov u mikroorganizmov i kletok zlokachestvennyh opuholej (Similarity of antigens in microorganisms and malignant tumor cells), Kiev: Naukova dumka, 1982, 247 p.

6. Smirnova V.V., Kudryavceva T.P., Nauch.-tekhn. byul., Novosibirsk, 1983, Issue 37, pp. 15–19. (In Russ.)

7. Gorbatov V.A. Byul. VIEV, Moscow, 1974, Issue 17, pp. 39–40. (In Russ.)

8. Fel’ V.Ya., Ivanov V.A., Vahtin Yu.B., Shvemberger I.N., Olenov Yu.M., Kletochnaya nasledstvennost’ i zlokachestvennyj rost, Leningrad, 1966, pp. 146–153. (In Russ.)

9. Kudryavceva T.P. Lejkoz zhivotnyh (Leukemia of animals), Moscow: Rossel’hozizdat, 1980, 156 p.

10. Smirnova V.V. Patomorfologiya, epizootologiya i voprosy immunologii gemoblastozov krupnogo rogatogo skota v Zapadnoj Sibiri (Pathomorphology, epizootology and immunology of bovine hemoblastoses in Western Siberia), Extended abstract of candidate’s thesis, Moscow, 1984, 24 p. (In Russ.)

11. Smirnova V.V., Kudryavceva T.P., Nauch.-tekhn. byul., Novosibirsk, 1983, Issue 37, pp. 15–19. (In Russ.)

12. Smirnov P.N., Trostyanskij I.V., Chydym S.M., Leonova M.A., Amirokov M.A., Innovacii i prodovol’stvennaya bezopasnost’, 2017, No. 4 (18), pp. 51–55. (In Russ.)


Review

For citations:


Smirnov P.N., Agarkova T.A., Razumovskaya V.V. LYMPHOID ORGANS IN LEUKEMIA AND OTHER PATHOLOGIES IN CATTLE. Innovations and Food Safety. 2022;(4):116-121. (In Russ.) https://doi.org/10.31677/2311-0651-2022-38-4-116-121

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ISSN 2311-0651 (Print)